New information is shedding light on the disturbing disappearance of Nancy Guthrie, as investigators examine the possibility that she was abducted from her home in the middle of the night.

According to information being reviewed by law enforcement, investigators are looking into signs that suggest Guthrie may have been taken from her bed while she was asleep. Authorities have also identified indications of forced entry at the residence, raising serious concerns about foul play in what was initially treated as a missing person case.

Sources familiar with the situation say Guthrie had been dropped off at her home on Saturday evening, January 31, after attending a church function. She arrived at approximately 9:45 p.m., marking the last confirmed time she was seen. There were no immediate reports of distress or unusual behavior at the time she returned home.

Alarm was raised the following morning when Guthrie failed to appear for Sunday church service. Family members and friends described her absence as highly unusual, prompting them to begin checking on her whereabouts. As concern grew, authorities were contacted to initiate a welfare check and subsequent investigation.

Inside the home, investigators reportedly found several troubling details. Guthrie’s front door was discovered unlocked. Her keys, purse, identification, phone, and daily, critical medication were all found inside the residence. Officials noted that the absence of these essential items strongly suggests she did not leave voluntarily.

The fact that Guthrie’s medication remained behind has been a particular focus for investigators and loved ones alike. Family members have emphasized that she would not intentionally leave without medication she depended on daily, further deepening fears that she may have been taken against her will.

In addition to the unlocked door and personal belongings left behind, sources say there were other alarming signs inside the home. However, authorities have not disclosed those details publicly, citing the integrity of the ongoing investigation.

The case has drawn widespread attention due in part to Guthrie’s family connections. She is the mother of Savannah Guthrie, a well-known public figure. Despite speculation, the Pima County Sheriff’s Office has declined to comment on whether investigators believe Nancy Guthrie was specifically targeted because of her relationship to her daughter.

Law enforcement officials have emphasized that the investigation remains active and fluid. Detectives are working to establish a precise timeline of events between Guthrie’s return home Saturday night and the time she was reported missing Sunday morning.

Authorities are also canvassing the surrounding neighborhood, urging residents to review home surveillance footage, doorbell cameras, and any other recording devices that may have captured unusual activity overnight. Even seemingly insignificant details, investigators say, could prove critical in determining what happened.

The request for community assistance underscores the seriousness of the case. Investigators believe that if an abduction did occur, there may be visual evidence in the area that has not yet been identified.

Friends and members of the local church community have described Guthrie as dependable and deeply involved in her faith, making her sudden disappearance all the more alarming. Several said her failure to attend Sunday service was immediately recognized as a red flag.

As the search continues, law enforcement has not confirmed whether there are any suspects or persons of interest. Officials have also not stated whether the forced entry signs indicate a struggle or a targeted intrusion, leaving many questions unanswered.

The uncertainty has been especially difficult for Guthrie’s family, who are facing the emotional toll of not knowing what happened. Loved ones have expressed hope for a miracle outcome, while acknowledging the growing concern as time passes.

Investigators stress that missing person cases involving possible abduction are treated with the highest level of urgency. Each hour is considered critical, particularly when there are indicators that the individual may be in danger.

Authorities are asking anyone in the area who may have seen or heard anything unusual during the overnight hours to come forward. Tips can be directed to the Pima County Sheriff’s Office, and officials say even partial information could help advance the case.

For now, the disappearance of Nancy Guthrie remains an open and deeply troubling mystery. As investigators continue their work, the community watches closely, hoping for answers — and for her safe return.