As investigators intensify the search for Nancy Guthrie, new insight from a neighbor is shedding light on the first chilling indication that something had gone terribly wrong the night she disappeared from her Tucson-area home.

Guthrie, 84, the mother of Savannah Guthrie, was last seen on January 31 around 9:30 p.m. at her residence near Skyline Drive and Campbell Avenue outside Tucson. She was reported missing the following day after she could not be reached.

According to a neighbor familiar with Guthrie’s routine, the first red flag appeared almost immediately. The neighbor said there were signs that did not align with Guthrie’s normal habits, prompting concern before law enforcement confirmed the possibility of a criminal act.

“She was very consistent,” the neighbor explained, describing Guthrie as someone who followed predictable routines and was mindful of her surroundings. When those routines were suddenly broken, it raised alarm among those who lived nearby.

When officers arrived at the home to conduct a welfare check, they encountered what authorities described as a scene that caused “grave concern.” Investigators later said evidence suggested Guthrie may have been forcibly removed from her home, escalating the case from a missing-person investigation to a suspected abduction.

The Pima County Sheriff’s Office has since confirmed that the disappearance is being treated as a potential criminal act. Deputies and detectives have been canvassing the neighborhood, speaking with residents, and collecting surveillance footage from home security and doorbell cameras.

The neighbor said the realization that something was seriously wrong set in when Guthrie did not respond as expected and when other subtle signs pointed to an abrupt disruption in her normal behavior. Those details were later shared with investigators as part of the door-to-door canvass.

Authorities have not publicly detailed the specific clues described by neighbors, but officials say community observations are playing a critical role in reconstructing the timeline of events leading up to Guthrie’s disappearance.

Police have also confirmed they are searching for a vehicle of interest believed to be connected to the suspected abduction. Investigators are reviewing footage from nearby streets and asking residents to report any unfamiliar vehicles seen in the area late on January 31 or early the following morning.

Neighbors described a heightened law enforcement presence in the area, with patrol cars and investigators visible throughout the neighborhood. Many residents have cooperated by providing camera access and sharing observations from the night Guthrie vanished.

The case has deeply unsettled the community, particularly given Guthrie’s age and the suggestion of a violent crime. Residents say the idea that someone could be taken from her home has left many on edge.

Authorities continue to urge the public not to speculate and to avoid spreading unverified information. Officials stress that while neighbor observations are valuable, conclusions must be based on evidence.

As the investigation continues, detectives are working to piece together Guthrie’s last known movements and determine who may be responsible. No suspects have been named, and police have not released a description of the vehicle of interest.

For now, the neighbor’s account stands as a haunting reminder of how quickly routine can give way to alarm — and how small, seemingly ordinary details can signal that something is terribly wrong.