A neighbor of Nancy Guthrie said his dogs mysteriously jolted him awake on two key nights linked to the 84-year-old’s disappearance from her Arizona home — behavior he insists is highly unusual and hasn’t happened since.

Jeff Lamie, who lives just a few houses from Guthrie’s Catalina Foothills home, told “Crime Stories with Nancy Grace” on Monday that his dogs suddenly woke him around 1 a.m. on Feb. 1 and forced him outside around the same time authorities believe the mom of “Today” show host Savannah Guthrie was taken.

“It could be a coincidence or it could be nothing,” Lamie said, noting his pets’ odd late-night behavior was “atypical,” especially for the one that is normally a “deep sleeper.”

“The dogs did rouse, and I took them out. I heard nothing or saw nothing, but you know, animals can be –especially dogs — can be hypersensitive, and we don’t know if there’s a correlation. We’ve shared it, and whether it helps with the timeline or in any way, we hope it is of some value.”

After reviewing security footage from his courtyard that night, he said one dog appeared to fixate on something in the distance before moving on.

He told Grace his canines also startled him awake on Jan. 11 — a date embattled Pima County Sheriff Chris Nanos recently flagged.

Nanos told KOLD on Monday that authorities are probing a possible incident at Guthrie’s Arizona home on Jan. 11, noting he believes “something occurred” two weeks before the abduction but refused to explain what evidence pointed investigators to that specific evening.

“It was unusual, and it seldom happens, and we’ve gone back to other dates we’ve been asked about to see if there’s a correlation,” Lamie said, referring to a police request for neighbors to review their surveillance footage for anything unusual.

“It hasn’t happened since,” the concerned resident said of his dogs’ midnight bathroom runs. “I don’t know if they heard something, smelled something, sensed something in some way, so we’ve obviously provided that information and I don’t know if it is of any help, but I hope that it is.”

Nanos’ startling revelation about Jan. 11 came just days after Guthrie’s three children urged anyone with information about their mother’s disappearance to come forward, clinging to hope as the search for her entered its seventh week.

Guthrie is believed to have been taken from her Tucson home during the early hours of Feb. 1.

She was reported missing after she failed to show up at her church group, and security footage recovered from her doorbell camera captured a masked man loitering around the doorstep the night police believe she was kidnapped.

Police have still not identified any suspects in the 51 days since she vanished.