
The investigation into the disappearance of 84-year-old Nancy Guthrie, mother of NBC “Today” show co-anchor Savannah Guthrie, has taken a dramatic and deeply unsettling turn. Authorities have reportedly recovered DNA belonging to her son-in-law, Tommaso Cioni, inside a vehicle towed from the property linked to the family home in the Catalina Foothills near Tucson, Arizona.
Nancy Guthrie vanished in the early hours of February 1, 2026, shortly after being dropped off at her residence by Cioni following a family dinner with her daughter Annie Guthrie, Cioni’s wife. What began as a missing persons case quickly escalated when blood confirmed to be Nancy’s was discovered on the front porch and around the home. Her pacemaker reportedly disconnected around 2:28 a.m., and doorbell cameras—some allegedly tampered with or disconnected—failed to capture clear footage of the critical moments.
Investigators impounded a vehicle associated with the family, focusing forensic efforts on potential evidence inside. The discovery of Tommaso Cioni’s DNA in the towed car has intensified scrutiny on the son-in-law, who was among the last people to see Nancy alive. Cioni, an AP biology teacher married to Annie for years and living nearby, drove his mother-in-law home that night, watching her enter through the garage before leaving.
Adding to the horror, sources indicate that dashcam or in-car video from the vehicle captured disturbing events from that fateful night. While details remain limited, the footage is said to document shocking occurrences that could shed light on what transpired after Nancy entered her home. This evidence, combined with blood traces and signs of possible forced tampering at the residence—including disconnected security devices and an open back door—has shifted the probe from a potential stranger abduction to a closer examination of family connections.
The Pima County Sheriff’s Department, assisted by the FBI, has released images and video of a masked, armed individual seen near the home in the early morning hours, tampering with cameras. Speculation has swirled online about links to known individuals, but no official suspect has been named publicly. Rewards have been offered for information, and searches have extended to nearby foothills and family properties, including repeated visits to Annie and Cioni’s home.
The case has gripped the nation, blending high-profile family ties with grim forensic clues. Blood evidence matches Nancy, yet no clear signs of robbery explain the scene. The presence of Cioni’s DNA in the vehicle raises urgent questions about movements that night and possible motives hidden within family dynamics.
As testing continues and more footage is analyzed, the mystery deepens. Was this a planned act, a panicked escalation, or something far more sinister? Authorities insist the investigation remains active, with everyone still considered in play. For now, the dashcam’s “horrifying” record stands as a haunting piece of the puzzle in what may be a tragic family betrayal.
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